Over a period of about twenty years Fred and Rose West abducted, tortured, raped and murdered an unknown number of girls, many of whom lay buried in the garden until the police dug them up. What motivated West to commit such terrible crimes? Was he born evil or did his upbringing make him this way? Did he do it for sexual kicks? Or, as some allege, did he supply the sacrificial victims to a black magic coven?

The world’s most prolific killer, Shipman is estimated to have killed 275 people, but the actual figure will never be known. The 57-year-old GP was given 15 life sentences to run concurrently for the murders, and four years for forging a will, but hung himself in his cell after he was sentenced. He always denied his crimes. When the police began investigating Dr Harold Shipman in September 1998 they struggled to understand him. How could a GP who was trusted and respected by more than 3,000 patients also be a killer who struck time after time with no obvious motive? The coroner speculated that ‘the only valid possible explanation for it is that he simply enjoyed viewing the process of dying and enjoyed the feeling of control over life and death, literally over life and death …’

Jeffrey Dahmer was a homosexual sexual deviant who raped, murdered and ate parts of 17 victims. Like other killers such as John Wayne Gacy, he managed to elude capture while continuing to carry out his crimes. Like every other sociopath serial killer in history he believed himself to be completely justified in his actions. Why does a Jeffrey Dahmer happen? How does a man become a serial killer, necrophiliac, cannibal and psychopath? Many of the theories would have you believe that the answers can always be found in childhood abuse, bad parenting, head trauma, foetal alcoholism and drug addiction. Perhaps in some cases these are contributing factors, but not for Jeffrey Dahmer…

Hearse driving redneck Donald Pee Wee Gaskins may only have stood 5'4" tall, but he would earn himself the nickname of the meanest man in America and become South Carolina's biggest mass murderer when police discovered his boasts of having his own private graveyard were real. Cops would eventually discover the bodies of 13 men women and children, but in prison Gaskins would claim to have killed more than a hundred - raping, torturing and then sinking their bodies in the swamps. And Gaskins would add to his tally in prison, pulling off the extraordinary murder of a death row inmate - blowing him up by remote control. But what created this feared psychopath and sexual sadist? Was it nature or nurture? The men that knew and pursued him, leading experts, and the loving daughter he confessed to examine whether Pee Wee Gaskins was born to kill?

When body parts began washing up on the beaches of a peaceful Californian seaside town, police realised someone was hunting, abducting, murdering and dismembering female co-eds. What they didn't realise was; the killer was in their midst - drinking with them at their favourite local bar. Cops considered the 6'9' inch Edmund Kemper a gentle giant, little did they know that as a teenager he'd murdered his grandparents, he'd fooled psychiatrists into releasing him from secure hospital after just 5 years, and while he was socialising with police officers he was living out his bizarre sexual fantasies with the corpses of young co-eds. Edmund Kemper would kill and dismember 6 young college girls before turning on his mother and her best friend. Was his mind was twisted by his upbringing in a broken home and volatile relationship with a domineering mother? Or was the Co-ed Butcher born to kill?

By the age of ten, heavy metal fan Richard Ramirez was sleeping in cemeteries. He would go on to spread terror throughout Los Angeles, preying on ordinary citizens as they slept in their homes. The Satan loving, drug fuelled burglar would rape, murder, and mutilate, taking pleasure in making his victims pray to Satan before him. Men, women, children and the elderly all fell victim as the police raced to catch the killer who defied all known theories about serial murder. So, was the Richard Ramirez born to kill? Warped by drugs? Or, was the Night Stalker schooled in murder during his poor childhood in the tough Texan border town of El Paso?

When the discovery of human flesh blocking the drains of an address in London led to the arrest of 37 year old civil servant Dennis Nilsen, police were staggered when he calmly told them he had killed at least 15 young men. At the time, Nilsen would go down in history as Britain's most prolific serial killer, and as police interviewed the matter-of-fact Scot, they uncovered the extraordinary story of a man obsessed with death since childhood. The lonely job centre executive would strangle his victims and keep their corpses for company, sitting them in chairs, talking to them and watching television together, before butchering burning or boiling the body-parts. Was Dennis Nilsen obsession with death fused during his childhood? Or, was his instinct to kill hard-wired from birth?

The Son of Sam would become the most notorious killer in New York's history. Shooting women or couples parked in lover's lanes, the mystery killer spread terror through the streets of the metropolis, leading young women to cut and dye their hair for fear of becoming the killer's next victim. Writing to the police and press, the Son of Sam would claim to relish his 'work' and that he was programmed to kill. A massive manhunt would lead police to David Berkowitz - a lonely young man, adopted at birth, who claimed he was commanded to do the devil's work by a neighbour's barking dog. So was the Son of Sam driven by demons? Wreaking a bitter revenge fuelled by mental illness? Or was he programmed from birth to be a serial murderer?

Profile of the 1970s armed robber and kidnapper.

In California in 1970, a doctor and his young family were executed and dumped in the swimming pool of their hilltop home. The killer believed that he was on a mission from God.

Featuring the killing of walkers in Yosemite National Park

Patrick Mackay is a British serial killer who confessed to murdering eleven people in the mid 1970s and considered by police to be a suspect in at least a dozen other killings over the previous two years.

Featuring a crime spree in Richmond, Virginia in 1979.

Profile of American serial killer H Clark.

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